For instance, Fabbri and collaborators confirmed that exosomes produced by lung cancer cells contain miRNA-2 l and miRNA-129a, which in turn bind to TLR family members, including mouse TLR7 and human TLR8, as ligands on immune cells, triggering TLR-dependent inflammatory reactions and promoting lung cancer cell proliferation [17]. The gene discussed is TLR8; the disease is lung cancer.