The results of multivariate analysis showed that age (HR = 1.334, 95%CI 1.045–1.704, P = 0.021), histological type (HR = 0.741, 95%CI 0.560–0.980, P = 0.036), SII (HR = 2.707, 95%CI 2.074–3.533, P < 0.001), ALb (HR = 0.385, 95%CI 0.283–0.525, P < 0.001), CEA (HR = 1.285, 95%CI 1.007–1.640, P = 0.044), CA125 (HR = 1.370, 95%CI 1.069–1.755, P = 0.013), WBC (HR = 1.361, 95%CI 1.047–1.770, P = 0.021), operation method, and TNM stage were all independent risk factors for the prognosis of GC patients (Table 2). Here, ALB is linked to gastric cancer.