CD4 and liver cancer: In addition, based on the CTD database, activated memory CD4 T cell-related genes were involved in 31 liver cancer-related pathways [e.g., CAMs, Th1 and Th2 cell differentiation, hematopoietic cell lineage] (Table 2), and CD8 T cell-related genes were involved in 36 liver cancer-related pathways [e.g., Th17 cell differentiation, Th1 and Th2 cell differentiation, and CAMs] (Table 3).