In terms of driver genes in Cancer Gene Census, focal amplified regions implicated the oncogenes PRDM16 and SKI at 1p36, MUC4 at 3q29, TERT at 5P15, TLX3, NPM1, FGFR4 and FLT4 at 1q35, CUX1 at 7p22, BRD3 and NOTCH1 at 9q34, HRAS at 11p15, CCND1 at 11q13, AKT1 at 14q32, KAT7 at 17q21, H3F3B at 17q25, GNA11, TCF3, MAP2K2, FSTL3 and SH3GL1 at 19p13, and U2AF1 at 21q22. The gene discussed is TLX3; the disease is cancer.