Intriguingly, lncRNA-IUR1 was expressed in a very low level in Bcr-Abl-positive cells from chronic myeloid leukemia patients as compared with that in normal subjects (Fig. 1E, F), which prompted us to explore the role of lncRNA-IUR1 in Bcr-Abl-induced tumorigenesis. The gene discussed is IUR1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.