In line with these results, tumors formed by lncRNA-IUR1 overexpressing K562 cells grew much slower than that formed by control cells in the xenograft mouse model, whereas enhanced expression of GATA3 in lncRNA-IUR1 overexpressing cells can reverse the inhibitory effect of lncRNA-IUR1 overexpression on xenografted tumor growth in mice (Fig. 8F). This evidence concerns the gene IUR1 and neoplasm.