Moreover, comparing B-ALL with CBD, the mRNA expression levels of ENSG00000170561 (IRX2), ENSG00000135333 (EPHA7), ENSG00000213934 (HBG1), ENSG00000170549 (IRX1) and ENSG00000102755 (FLT1) were upregulated (Fig. 2C), while ENSG00000169429 (CXCL8), ENSG00000123689 (GOS2), ENSG00000163421 (PROK2), ENSG00000163739 (CXCL1), ENSG00000112715 (VEGFA) in B-ALL were downregulated (Fig. 2D). This evidence concerns the gene IRX1 and precursor B-cell acute lymphoblastic leukemia.