Subgroup analysis showed that high expression levels of SNHG7 were also significantly associated with unfavorable OS in digestive system cancer (HR = 2.31, 95% CI: 1.90–2.80, p<0.001) and non-digestive system cancer (HR = 2.67, 95% CI: 2.12–3.37, p<0.001). This evidence concerns the gene SNHG7 and digestive system cancer.