Univariate Cox regression analysis showed that the expression levels of IGFBP2 (P-value = 0.002), VIRMA (P-value = 0.039), IGFBP1 (P-value <0.001), HNRNPC (P-value = 0.009), HNRNPA2B1 (P-value = 0.004), YTHDF2 (P-value <0.001), and IGF2BP3 (P-value = 0.005) were protective factors for patients with sarcoma (Supplementary Figure 1B and Supplementary Table 2). The gene discussed is IGF2BP3; the disease is sarcoma.