Among them, Vir-Like m6A methyltransferase associated (VIRMA), METTL14, METTL3, Wilms tumor 1 (WT1)-associated protein (WTAP), fragile-X mental retardation 1 (FMR1), HNRNPA2B1, HNRNPC, IGF2BP3, LRPPRC, YTH domain containing (YTHDC)-1, YTHDC2, and FTO were highly expressed in normal tissues, while RBM15, RBM15B, ZC3H13, ELAVL1, IGF2BP1, YTH m6A RNA-binding protein (YTHDF)-1, YTHDF3, and ALKBH5 were highly expressed in sarcoma tissues. The gene discussed is IGF2BP1; the disease is sarcoma.