NLRP3 and COVID-19: Fourth, although the differentiated role of NLRP3 inflammasome in specific cell types such as macrophage, monocytes, and dendritic cells in COVID-19 patients has been preliminarily shown by single cell RNA-seq,34, 57, 58 it would be rewarding to investigate the role of NLRP3 inflammasome and related signaling pathways in individual immune cells in COVID-19 context.