Intravesical administration of KSI-3716 at a dose of 5 mg/kg could significantly inhibit bladder tumor growth in murine model.147 KSI-1449 and KSI-2302 can similarly inhibit the formation of c-Myc/Max/DNA complex, thereby preventing the biologic activity of c-Myc.148. This evidence concerns the gene MYC and urinary bladder neoplasm.