That is, though both genetic variants in the coding and non‐coding regions of ITIH3 are associated with schizophrenia, these variants confer risk of schizophrenia via different mechanisms (i.e., risk variants in ITIH3 coding region confer schizophrenia susceptibility by altering protein function, while risk variants in non‐coding (ITIH3 intron) regions may contribute to schizophrenia risk by modulating the expression of distal gene (or genes)). Here, ITIH3 is linked to schizophrenia.