NOS2 and colitis: Beyond bone fide infection models and chemically induced colitis, antimicrobial IgG is observed in a variety of spontaneous colitis models in immune‐replete mice, including Il10−/−,160 C3H/HeJBir161 and Nod2−/−Cybb−/− mice,162 as well as mice strains that exhibit increased microbial penetrance, such as Myd88−/−Ticam−/− and Nos2−/−Cybb−/− double‐deficient mice.163