ABCA1 and fatty liver disease: Sodium butyrate induced Abca1 mRNA and ABCA1 protein levels in murine RAW264.7 cells, accompanied by an increased efflux of cholesterol from these cells.419 This induction was reflected by increased ABCA1 protein content in vivo, reduced plasma cholesterol and triglyceride levels, and reduced aortic atherosclerotic lesions and hepatic steatosis in high fat diet-fed Apoe knock-out C57BL/6 mice.