ABCA1 and papillary renal cell carcinoma: In addition, the LXR agonist LXR623 induced ABCA1 mRNA and ABCA1 protein levels in two human renal adenocarcinoma cell lines334 as well as Abca1 mRNA levels in vivo in C57BL/6 mice.378 This induction was reflected in reduced intracellular cholesterol and triglyceride levels.