ABCA8 and pancreatic neoplasm: ABCA8 mRNA and ABCA8 protein content were induced by gemcitabine in PANC-1 and CFPAC-1 human pancreatic cancer cells.221 In rat liver, an induction of Abca8 was demonstrated via microarray analysis of cDNA when the rats were exposed to polyethyleneglycol-block-polylactide nanoparticles.433