For example, chemokine (C‐C motif) ligand 5 (CCL5) induces the formation of eukaryotic initiation factor 4F translation initiation complex in an mechanistic target of rapamycin (mTOR)‐dependent way, which mediates the quick upregulation of cyclin D1, c‐Myc, and defender against cell death‐1 (Dad‐1) protein expression to promote tumor cell proliferation in breast cancer.384. This evidence concerns the gene CCND1 and neoplasm.