In many types of tumors, including melanoma, breast cancer, and liver cancer, the expressions of autophagy‐related proteins light chain 3 and beclin‐1 in tumor tissues of patients with distant metastasis are higher than in tumor tissues of patients with non‐metastatic tumor, suggesting that autophagy is closely related to tumor metastasis.209, 210, 211. Here, BECN1 is linked to neoplasm.