In nasopharyngeal carcinoma (NPC), EVs migrate from highly metastatic to poorly metastatic NPC cells, mediate intercellular communication, and enhance the metastatic potential of poorly metastatic NPC cells by inducing the up‐regulation of epidermal growth factor receptor (EGFR) and down‐regulation of reactive oxygen species (ROS).191. The gene discussed is EGFR; the disease is nasopharyngeal carcinoma.