DCN and neoplasm: As shown in Figures 6H–6J, intratumoral administration of OAV-DEC led to the secretion of human decorin in the injected tumors with induction of increased intratumoral murine IFN-γ protein and decreased murine TGF-β compared with OAV, indicating that intratumoral secretion of decorin promoted an inflammatory response in the tumor microenvironment.