CDKAL1 and type 2 diabetes mellitus: To study the relationship between the variation of CDKAL1 RS10946398 locus and the susceptibility to T2DM in different populations, 14 sets of data were finally used for meta-analysis through data investigation and screening, and 13 sets of data showed that the CDKAL1 RS10946398 locus was significantly correlated with the incidence of T2DM; for example, a study by Nfor et al. showed a significant association between CDKAL1 RS10946398 and T2DM in Taiwanese.