Positive aPL sera from COVID-19 patients induced upregulation of the cell adhesion molecules E-selectin, vascular cell adhesion molecule 1 (VCAM-1), and intracellular adhesion molecule 1 (ICAM-1) in HUVECs, which was abolished by total IgG depletion from the COVID-19 sera (45). This evidence concerns the gene VCAM1 and COVID-19.