ZFP91 and hypertrophy: Additionally, differentiated spliced TFs also function in cardiac fibrosis (e.g., KLF6) (19), angiogenesis (e.g., VEZF1) (20), cardiac structure and contractile function (e.g., VEZF1) (21), cardiac hypertrophy, inflammation, and regulatory T-cell homeostasis (e.g., ZFP91) (22–24) (Figure 7A).