In TNM I-II and TNM III-IV subgroups, HCC patients with low-FHPS had better OS compared with HCC patients with high-FHPS, and the same results were obtained for whoI-II and WHOIII-IV, AFP < 400 and >= 400 ug/ L, female and male, age < 65 and age >= 65 subgroups (Figures 4F–O). Here, AFP is linked to hepatocellular carcinoma.