Examples include treatment of Chang liver cells with the chemical 1,10-phenanthroline (Jo et al., 2015), addition of H2O2 to HepG2 or HEK-293 cells (Zhang et al., 2013), treatment of mouse embryonic fibroblasts with 3-methyladenine (Ivashchenko et al., 2011), loss of GRP75 in neuroblastoma cells (Jo et al., 2020b), peroxisomal KillerRed-mediated ROS production in NIH/3T3 cells (Chen et al., 2020), suppression of catalase expression or activity in serum-starved HepG2 or RPE1 cells (Lee et al., 2018), and prolonged fasting of catalase-deficient mice (Dutta et al., 2021). Here, CAT is linked to neuroblastoma.