The role of NEU1 has been studied in different cardiovascular diseases, including atherosclerosis, ischemic/reperfusion injury, cardiac hypertrophy, and heart failure (Heimerl et al., 2020; Chen et al., 2021), (Gökmen et al., 2000; Süer Gökmen et al., 2006; Yang et al., 2012; Gayral et al., 2014; White et al., 2018). This evidence concerns the gene NEU1 and heart failure.