YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) is a direct downstream target of miR-340-3p, H19 regulates the breast cell progression miR-340-3p/YWHAZ axis, and the H19/miR-340-3p/YWHAZ axis altered EMT phenotype in breast cancer metastasis and invasion by regulating β-catenin expression, accompanied with changed expression of E-cadherin, Slug, Snail, Vimentin, Cyclin D1, and c-Myc (Yan et al., 2020). The gene discussed is YWHAZ; the disease is breast cancer.