FBLN1 and type 2 diabetes mellitus: In accordance with the results of the in vitro and in vivo studies, the miR-1269b–FBLN1 axis was shown to participate in the mechanism of HG-induced exosome-mediated kidney injury, suggesting that urinary exosomal miR-1269b and FBLN1 could be used to predict kidney injury in clinical patients with T2DM.