For example, in Alzheimer’s disease, the post-transcriptional regulation of BACE1 involves miR-485-5p, and the specific antisense transcription of BACE1 forms lncRNA-BacE1-As, which compete with lncRNA-Bace1-As to bind to the binding sites of related mRNAs (Faghihi et al., 2010). Here, BACE1 is linked to early-onset autosomal dominant Alzheimer disease.