Interestingly, high percentage of colocalization between ITGB1 and PXN or YWHAZ was observed in HCC cells, indicating that ITGB1 might interact with PXN and YWHAZ (Figure 6E, G, H, J, Supplementary Figure S5A, B, E, F; Supplementary Figure S6A, B, E, F). The gene discussed is ITGB1; the disease is hepatocellular carcinoma.