According to the basal expression levels of CPEB4 compared in various RCC cell lines (Figure 1D), ACHN cells (CPEB4-high) with CPEB4 stable knockdown and 786O cells (CPEB4-low) with CPEB4 stable overexpression were used to verify the function and mechanism of CPEB4 in the follow-up experiments. Here, CPEB4 is linked to renal cell carcinoma.