IL6 and non-small cell lung carcinoma: In this study, we examined the effect of hMSCsmalat−1-EVs on OA inflammation and found that hMSCsmalat−1-EVs can reduce IL-6 levels in the OA model, in agreement with the results of Jiyong Zhang et al. (Zhang et al., 2020) Ruizhang et al. found that lncRNA malat-1 in EVs promoted proliferation and migration of non-small cell lung cancer cells (Zhang et al., 2017).