ID1 and B-cell non-Hodgkin lymphoma: Jobsri et al., 2015 reported a study in which PVX was conjugated to an idiotypic (Id) tumor-associated antigen (TAA) recombinant through a biotin/streptavidin linker, that elicited a 7 times higher anti-Id IgG response compared to Id alone in a mouse B-cell lymphoma model.