CP and Liver abscess: These results indicate that expression of EhArfX2T28N, which caused impairment of lysosome biogenesis and regulation of CP trafficking, also resulted in a reduction in the ability of liver abscess formation despite comparable rate of growth and erythrophagocytosis in vitro. Overexpression of EhArfX2WT-HA upon v-HM1 genetic background did not have an additive effect on liver abscess formation.