In this case, the patient manifested unusual clinical presentations (fatigue, splenomegaly, anemia, no fever, hemorrhages, or concurrent infections), which frequently occur in individuals with low CD4+ T-cell counts (23.01%) (Bimal et al., 2008; Garg et al., 2009; Santos-Oliveira et al., 2010). The gene discussed is CD4; the disease is Splenomegaly.