Approved targeted therapies that have been tested in the post-allo-HCT relapse setting include midostaurin and gilteritinib for FLT3+ AML, (73, 74) enasidenib for IDH2+ AML (75), and ivosidenib for IDH1+ AML (76). The gene discussed is FLT3; the disease is acute myeloid leukemia.