IDH1 and acute myeloid leukemia: In a trial in relapsed/refractory IDH1-mutated AML that treated 36 post-transplant patients at the FDA-approved dose, ivosidenib produced an overall response rate (CR, CRi, CRp, or bone marrow CR) of 41.6% without any differences in response noted based on most baseline clinical characteristics, which included prior allo-HCT (76).