ITGA5 and central nervous system cancer: A higher expression level of ITGA5 was associated with poorer outcomes in patients with glioma (TCGA: HR = 5.564, 95%CI = 4.203–7.367, p < 0.0001; CGGA: HR = 2.899, 95%CI = 2.433–3.454, p < 0.0001) (Figure 4B).