The NF-κB signaling pathway comprises a family of five transcription factor subunits (p65/RelA, c-Rel, RelB, p50/NF-κB1, and p52/NF-κB2), which are key regulators of tumor cell growth, proliferation, metastasis, and chemotherapy resistance (30, 31). Here, NFKB1 is linked to neoplasm.