MUC1 overexpression, in association with MUC1-C, contributes to activation of the nuclear factor Kappa-activated B cells (NF-κB) (52), Wnt/β-catenin/TCF4 (transcription factor 4) (53), and STAT1/3 pathways in NSCLC (54). This evidence concerns the gene TCF4 and non-small cell lung carcinoma.