The multivariate Cox regression analysis indicated us that good differentiation (hazard ratio, [HR] =0.386; 95% confidence interval [CI]: 0.182-0.816; p=0.013), N0 state (HR=0.121, 95% CI: 0.023-0.629, p=0.012), IIIA stage (HR=0.327, 95% CI: 0.160-1.669, p=0.002) and low YBX1/MUC1 coexpression (HR=0.241; 95% CI: 0.119-0.441; p<0.001) were independent prognostic factors of overall survival in lung adenocarcinoma (Table 4). This evidence concerns the gene MUC1 and lung adenocarcinoma.