Moreover, LAT2 (HR: 0.525901, 95% CI: 0.320208-0.863728, p-value = 0.011127) and HOOK2 (HR: 0.458976, 95% CI: 0.25448-0.827801, p-value = 0.009654) were protective factors for laryngeal cancer. This evidence concerns the gene HOOK2 and laryngeal carcinoma.