ELK3 and central nervous system cancer: Based on the CGGA microarray database, multivariate regression analysis indicated that ELK3 (P = 0.030, [HR] = 1.341 [95% CI [1.029–1.747])), PRS type (P = 0.013, [HR] = 1.510 [95% CI [1.091–2.090])), and grade (P < 0.001, [HR] = 3.226 [95% CI [1.898–5.481])) could be used as independent risk factors for poor prognosis of gliomas patients (Figure 2H).