Further investigation of these single-cell specific TP GBM genes revealed signaling pathways such as oxytocin, chemokine, mTOR, phosphatidylinositol, sphingolipid, Ras, hedgehog and mechanisms such as steroid hormone biosynthesis, inositol phosphate, glycerophospholipid, purine metabolism, endocytosis choline metabolism in cancer, CAMs etc. to be governed by the upregulated genes unique to the cell types. The gene discussed is MTOR; the disease is glioblastoma.