MDSCs are characterized by a CD11b+Gr1+ phenotype, and can be further classified into monocytic (mMDSC, CD11b+Ly6ChighLy6G-) and granulocytic (gMDSC, CD11b+Ly6G+Ly6Clow) subpopulations in tumor-bearing mice 7. This evidence concerns the gene ITGAM and neoplasm.