In addition, the Kaplan-Meier curve shows that the OS (P=0.034, Fig. 3B), as well as the disease-free survival (P=0.024, Fig. 3C) of HCC patients with SNRPD1 alterations (n=25), was poorer than without SNRPD1 alterations (n=322). The gene discussed is SNRPD1; the disease is hepatocellular carcinoma.