We performed the Kaplan-Meier analysis in the GEPIA database and results demonstrated that high SNRPD1 expression in patients with HCC correlated with shorter overall survival (HR=2, P<0.001; Fig. 2C) and disease-free survival (HR=1.4, P=0.016; Fig. 2D). This evidence concerns the gene SNRPD1 and hepatocellular carcinoma.