Meanwhile, the multivariate cox regression revealed that TNM staging (HR (95%CI): 1.682(1.049-2.699); P=0.031), Vascular invasion (HR (95%CI): 1.861(1.122-3.087); P=0.016), Tumor encapsulation (HR (95%CI): 0.209(0.129-0.338); P<0.001), and high SNRPD1 protein expression (HR (95%CI): 1.735(1.070-2.813); P=0.026) were independent risk factors (Table 4). Here, SNRPD1 is linked to neoplasm.