In addition, H19 promotes the migration and invasion of NSCLC cells through regulation of cellular signaling pathway proteins, such as metastasis associated in colon cancer1 (MACC1), epidermal growth factor receptor (EGFR), β-catenin, and extracellular-signal-regulated kinase1/2 (ERK1/2) 77. This evidence concerns the gene H19 and non-small cell lung carcinoma.