CXCL12 and colorectal adenocarcinoma: In previous studies, proliferation of the HT-29 cell line, a human colorectal adenocarcinoma cell line, was reduced by 5-FU or oxaliplastin treatment, but CXCL12-rich medium by coculture with a follicular dendritic cell line HK prevented the inhibitory effects of the chemotherapy drugs 57.