The mRNA expressions of FRGs in HCC with and without BAP1 mutation were demonstrated in Figure 5A. The expression of GXP4 and CS was significantly higher in BAP1 mutated HCC than in non-mutated HCC, while the expression of ALOX15, FDFT1, NCOA4, DPP4 was significantly lower in BAP1 mutated HCC than in non-mutated HCC, indicating that ferroptosis was promoted in non-mutated HCC (*p<0.05, **p<0.01, ***p<0.001). The gene discussed is ALOX15; the disease is hepatocellular carcinoma.