PVT1 and familial pancreatic carcinoma: Studies have confirmed that in pancreatic cancer, miR-519d can inhibit tumor growth by regulating the Wnt/β-catenin signaling pathway 16, and lncRNA plasmacytoma variant translocation 1 (PVT1) can exert tumor suppression effects through the miR-519d/HIF-1α axis 17.