It is worth noting that in the qRT-PCR analysis, these m6A-related lncRNAs, AL135999.1 and AL049840.4, were differentially expressed between CRC tissues and NATs, and our experimental results indicate that AL135999.1 may be related to METTL3-mediated m6A modification in CRC. The gene discussed is METTL3; the disease is colorectal carcinoma.