Furthermore, lithium is known to be used in the treatment of ASD (Mintz and Hollenberg, 2019) and BD (Berk et al., 2017) and was proposed at the preclinical level for FXS, since several phenotypes of adult Fmr1-KO mice are rescued by lithium treatment (Berk et al., 2017). This evidence concerns the gene FMR1 and fragile X syndrome.