NEK4 and Behcet disease: To date, cross-disorder analyses have been conducted in European samples and genes such as NEK4, GNL3, NCAN, and ZNF804A etc. were found to be risk genes for both SZ and BD (Ruderfer et al., 2014; Chang et al., 2017; Bipolar Disorder Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2018; Yang et al., 2020), but genes affecting the risk of both disorders in East Asian populations remain largely unclear.