As IgAD has been suggested to be associated with risk for these autoimmune disorders (Wang et al., 2011) and asthma (Urm et al., 2013), our observation suggest a potentially shared common genetic regulatory pathway in the cohorts carrying the HLA-B*08:01-DRB1*03:01-DQB1*02:01 risk haplotype. This evidence concerns the gene HLA-B and asthma.