FER was previously reported to be involved in ROS burst signaling to modulate the reproduction and the bacterial defense (Keinath et al., 2010; Kessler et al., 2010; Yu et al., 2012; Shen et al., 2017; Stegmann et al., 2017), and the infection of RKNs also accompanied with ROS burst (Wang et al., 2019). The gene discussed is FER; the disease is infection.